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ASH Annual Meeting and Exposition

ASH Poster Walks

 ASH Annual Meeting Poster Walks highlight cutting-edge emerging science in hematology during the meeting. A total of seven “walks” will be featured during the meeting with some taking place virtually and others taking place in person in collaboration with the Blood Journal Studio. In general, both the virtual and in-person Poster Walks can contain up to six posters and are designed to include a brief overview of the selected abstracts, followed by an interactive question-and-answer period between the session organizers, abstract authors, and audience.



ASH Poster Walk on Inherited Bleeding Disorders Hosted by Blood Vessels, Thrombosis & Hemostasis (For In-person Participants)

Saturday, December 6, 2025, 11:15 a.m. - 12:15 p.m.
Orange County Convention Center, West Hall B3-B4 – Blood Journal Studio

This poster walk will showcase the latest clinical studies in inherited bleeding disorders, with a particular emphasis on advancements in diagnosis and management. Attendees will benefit from discussions focused on understanding novel diagnostic tools, personalized treatment approaches, and strategies to overcome barriers in care for conditions like hemophilia and von Willebrand disease. By highlighting the intersection of equity topics, such as women's health and global hematology, the walk aims to foster a more inclusive perspective on inherited bleeding disorders, ultimately promoting better patient outcomes worldwide.

Organizer:

Nathan Connell, MD, MPH
Harvard University
Cambridge, MA

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ASH Poster Walk on Chemotherapy-Free Treatments for Indolent and Aggressive B-cell Non-Hodgkin Lymphoma Hosted by Blood Neoplasia (For In-person Participants)

Sunday, December 7, 2025, 8:00 a.m. - 9:00 a.m.
Orange County Convention Center, West Hall B3-B4 – Blood Journal Studio

Chemotherapy-free options are becoming increasingly available for patients with indolent and aggressive B-NHL. Multiple trials are investigating their safety and efficacy, finally challenging the paradigm that chemotherapy is here to stay. This is very significant not only for science, but also from a patient perspective. Spotlighting the most promising agents and combinations, which may change clinical practice in the near future, is now crucial.

Organizer:

Paolo Strati, MD
The University of Texas MD Anderson Cancer Center
Houston, TX

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ASH Poster Walk on Novel and Emerging Therapeutics in Erythrocyte and Iron Disorders Hosted by Blood Red Cells & Iron (For In-person Participants)

Sunday, December 7, 2025, 11:15 a.m. - 12:15 p.m.
Orange County Convention Center, West Hall B3-B4 – Blood Journal Studio

A more precise, mechanism-driven approach to treating red blood cell and iron/heme disorders is urgently needed. This poster walk showcases cutting-edge therapeutic strategies, from small-molecule activators and mRNA delivery platforms to gene-editing technologies and next-generation hemoglobin-modulating agents. These novel and emerging therapeutic strategies are designed to improve key disease parameters in disorders of erythropoiesis and iron metabolism, including Diamond–Blackfan anemia, autoimmune hemolytic anemia, hemochromatosis, sickle cell disease, and refractory thrombocytopenia.

Organizer:

Patrick Gallagher, MD
The Ohio State University
Columbus, OH

Laura Silvestri, PhD
San Raffaele Scientific Institute & Vita-Salute University
Milan, IT

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ASH Poster Walk on Rewiring Immune Effector Cells: Emerging Strategies to Boost Cancer Immunotherapy Hosted by Blood Immunology & Cellular Therapy (For In-person Participants)

Monday, December 8, 2025, 8:00 a.m. - 9:00 a.m.
Orange County Convention Center, West Hall B3-B4 – Blood Journal Studio

The tumor microenvironment presents significant metabolic and immunosuppressive challenges that limit the effectiveness of adoptive T cell therapies. Recent studies, including our work on the medium-chain fatty acid receptor GPR84, demonstrate that reprogramming T cell metabolism can enhance persistence, reduce exhaustion, and improve antitumor responses across various cancer models. This Poster Walk will bring together novel findings focused on metabolic modulation, cellular engineering, and immune reprogramming strategies that aim to optimize T cell function for therapeutic purposes. By highlighting innovative approaches, from receptor targeting to nutrient sensing and mitochondrial fitness, this session will benefit researchers and clinicians seeking next-generation solutions to enhance cancer immunotherapy. Attendees will gain insight into emerging mechanisms and translational strategies that can inform both preclinical and clinical development of improved T cell-based treatments.

Organizer:

Anamaria Morales-Alvarez, PhD
University of Central Florida
Orlando, FL

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ASH Poster Walk on Leukemia in Latin America: Bridging Gaps in Genetics, Access, and Innovation Hosted by Blood Global Hematology (For In-person Participants)

Monday, December 8, 2025, 12:30 p.m. - 1:30 p.m.
Orange County Convention Center, West Hall B3-B4 – Blood Journal Studio

This poster walk highlights the urgent need to improve leukemia outcomes in Latin America by addressing region-specific challenges in genetics, access to care, and treatment equity. Latin American populations are highly diverse and frequently underrepresented in global research, which limits the applicability of existing therapeutic protocols. The walk emphasizes the importance of generating region-specific data, studying local genetic profiles, and adapting emerging technologies in cost-effective and sustainable ways that match the reality of Latin American health systems. Attendees will gain a deeper understanding of existing gaps in research infrastructure, clinical trial participation, and access to innovative therapies. Ultimately, this poster walk aims to define concrete priorities for regional data generation, collaborative research, and sustainable implementation strategies to improve leukemia diagnosis and treatment in Latin America.

Organizer:

Melanie Castro Mollo, MD, MS
Icahn School of Medicine at Mount Sinai
New York, NY

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ASH Poster Walk on Population Health and Access to Care

Wednesday, December 11, 2025, 10:00 a.m. - 11:00 a.m.
Virtual Program

This Poster Walk will highlight works that investigate structural barriers impacting provision of care across hematology for patients from underserved or special populations. In particular, the walk will spotlight research (featured in the posters) that mitigates barriers and extends access to optimal care across populations. The featured posters will outline work being done to address unique care delivery challenges impacting patients, donors, and caregivers from specific vulnerable populations. It will serve to connect stakeholders in population health in hematology and facilitate discussions on the state of population health research in the field.

Organizer:

Warren Fingrut, MD, MPH
The University of Texas MD Anderson Cancer Center
Houston, TX

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ASH Poster Walk on State of the Art Artificial Intelligence in Hematology

Wednesday, December 10, 2025, 5:00 p.m. - 6:00 p.m.
Virtual Program

Over the past decade, interest in developing artificial intelligence (AI) tools to augment clinical decision-making has surged. While the integration of these techniques into routine hematologic practice remains a developing frontier, the capacity for AI to refine disease diagnosis, prognosis, and therapeutic strategy is becoming increasingly evident. This Poster Walk highlights the trajectory of this rapidly growing field through six pivotal studies utilizing machine learning, computer vision, and large language models (LLMs).

The session will examine foundational advancements, including federated learning frameworks for synthetic data generation and AI-driven platforms for identifying novel drug targets. We will further explore emerging clinical applications, such as enhancing acute leukemia management through long-read whole genome sequencing, automating the morphological diagnosis of cutaneous lymphoma, and utilizing machine learning to detect prognostic markers in CLL karyotypes. Finally, we will discuss the implementation of verifiable, guideline-based clinical decision support systems. Collectively, these works illustrate how AI is evolving from theoretical frameworks toward actionable clinical and translational applications.

Organizer:

Andrew Srisuwananukorn, MD
The Ohio State University
Columbus, OH

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